Obesity research: Tesofensine and NS2359 drug family for weight loss - Better to block three receptors than only 5HT2c? Nah.

Friday, May 30th, 2008

So far, lorcaserin is the only weight loss drug in the near future that makes commercial sense to me, not to say it is the most wonderful drug in the world and the science is, imo, sort of a yawner.
I keep an eye out for better weight loss drugs on the horizon — so here’s [...]

Power trips powered by dopamine

Monday, January 21st, 2008

The rewarding effect of aggression is reduced by nucleus accumbens dopamine receptor antagonism in mice.Couppis MH, Kennedy CH.Psychopharmacology (Berl). 2008 Jan 8 [Epub ahead of print]
I sat next to someone the other day wearing a t-shirt that said:

Of course, I had to sit and do the full analysis of that one for a while. I [...]

From NYT City Room: Would-Be Jumper Sues Empire State Building

Tuesday, January 15th, 2008

 
From the NY Times:
 

N.Y./Region
City Room: Would-Be Jumper Sues Empire State Building
By Anemona Hartocollis
Published: January 15, 2008
The professional parachute jumper who tried to leap off the city’s tallest building in 2006 released a video that shows him struggling with security guards and police officers on the observation deck.

Sphere: Related Content

Love advice for the ladies: Watch out for men born in winter, especially Swedish ones

Monday, November 26th, 2007

Ladies: if you are marrying a man born in the winter, keep a closer eye on him than if you are marrying a man born in the summer, fall, or spring.
 

Gabriel Max, “The Lion Bride,” (via NYPL Digital Gallery)
Men having “thrill-seeking” genes who are born in winter are more “venturesome” than those born [...]

Neurological Correlates: Apathy

Saturday, September 29th, 2007

Clin Neurol Neurosurg. 2007 Sep 25; [Epub ahead of print]

Striatal dopamine transporter levels correlate with apathy in neurodegenerative diseases A SPECT study with partial volume effect correction.
David R, Koulibaly M, Benoit M, Garcia R, Caci H, Darcourt J, Robert P.
Centre Mémoire de Ressource et de Recherche, CHU Nice, France.
OBJECTIVES: The aim of the [...]

Neurological Correlates: Neuromarketing, playing to the dopamine crowd

Tuesday, September 25th, 2007

Screenshots of (top) on-line gaming, and (bottom) on-line stock trading

J Gambl Stud. 2007 Mar 30; [Epub ahead of print]

Dopamine Genes and Pathological Gambling in Discordant Sib-Pairs.
Sabbatini da Silva Lobo D, Vallada HP, Knight J, Martins SS, Tavares H, Gentil V, Kennedy JL.
Laboratory of Medical Investigation (LIM-23)—Psychopharmacology, Department and Institute of Psychiatry, [...]